In short. A muscle relaxant changes movement and filler changes volume. For any given line one of them is usually the dominant answer, and the assessment tells you which.

Key points

  • Where two treatments are being considered, staging them makes it possible to know what produced what.
  • A first visit that changes movement and volume in the same area at the same time leaves no way to judge the contribution of either, which matters if a correction is ever needed.

Patients often arrive asking for one treatment when the other is the better answer, and the difference between them is easy to state. A muscle relaxant changes movement. Filler changes volume. A line is produced by some combination of the two, plus the skin itself, and the assessment decides which component dominates.

Movement-dominant lines

Frown lines between the brows, horizontal forehead lines and crow’s feet at the outer eye are generated by muscles folding the skin. They fade or soften when the face is completely at rest. These are the classic muscle-relaxant targets, and volume added to them achieves little because volume was never the problem.

Volume-dominant folds

Nasolabial folds, the lines running from the nose to the mouth, and the hollows that appear under the eyes and along the mid-face are usually the result of volume loss and tissue descent rather than muscle activity. Filler is the relevant tool. Treating them with a muscle relaxant alone addresses a component that may not be the dominant one.

Lines that are both

Many lines are mixed. A long-standing frown line may have a dynamic component and a static one, and a fold may be deepened both by movement and by volume loss. In those cases a combined plan is often the honest answer, and the useful question is which component to address first rather than whether to combine at all.

Do not do both at once on a first visit

Where two treatments are being considered, staging them makes it possible to know what produced what. A first visit that changes movement and volume in the same area at the same time leaves no way to judge the contribution of either, which matters if a correction is ever needed.

Skin-quality lines

Fine lines around the mouth, lines from sun damage and the surface texture changes of ageing skin are neither movement nor volume problems. They are skin problems, and the relevant options are topical care, energy-based treatment and microneedling. Injecting either a muscle relaxant or filler into them typically produces disappointment.

The risk difference

The two are not equivalent in risk. A muscle relaxant’s common unwanted effect is a temporary brow or eyelid change that resolves, and there is no reliable way to reverse it early. Filler’s most serious risk is vascular occlusion, in which filler blocks a blood vessel; it is a time-critical emergency that can cause skin loss and, rarely, vision loss. Where filler is proposed, the plan should include what would be done if that happened, and where it ranks against the alternative.

Get assessed rather than choosing for yourself if

  • You have already decided which product you want without an examination.
  • The line you care about is present at rest, and you expect it to disappear.
  • You are considering filler in the same session and no one has discussed vascular risk with you.

Related reading

Frequently asked questions

Can a line need both?

Yes. A line that is both folded by movement and deepened by volume loss may respond best to a combined plan, and the two treatments address different components. Combining adds the risks of filler to those of a muscle relaxant, so it is planned as one sequence rather than two separate decisions.

Which lasts longer?

Filler results generally last longer than botulinum toxin results, though both are temporary and both vary by area and substance class. Neither is permanent, and both require maintenance if the result is to continue.

What if I am not sure which my line is?

That is exactly what the assessment is for. Look at your face completely at rest: a line that fades at rest is movement-dominant, while one that stays is volume- or skin-dominant. Assessment confirms it and decides the plan.

Risks & Limitations

  • Temporary brow or eyelid droop after treatment, which resolves as the effect wears off.
  • Bruising, swelling or a brief headache at and after the injection sites.
  • Asymmetry, or an unwanted change in expression, which may need review before it settles.
  • All botulinum toxin results are temporary and maintenance treatment is required.
  • Where filler is injected in the same session, vascular occlusion — a time-critical emergency that can cause skin loss and, rarely, vision loss — is an additional risk.
  • No outcome can be guaranteed. Results vary with anatomy, movement pattern and healing.

When to Seek Care

  • Difficulty breathing, difficulty swallowing or slurred speech after treatment — seek emergency care.
  • Drooping eyelid, double vision, or weakness spreading beyond the treated area.
  • Severe pain, or skin turning white, grey, mottled or dusky after a filler injection — a vascular emergency.
  • Any change in vision — seek emergency care immediately.
  • Fever, spreading redness, warmth or pus at an injection site.

References & Further Reading

  • American Academy of Dermatology (AAD) — neurotoxin and injectable safety information
  • American Society of Plastic Surgeons (ASPS) — injectable guidance
  • U.S. Food and Drug Administration (FDA) — approved neurotoxin products and safety communications
  • National Medical Products Administration (NMPA, China) — approved product status
  • Chongqing West District Hospital — Plastic Surgery & Aesthetics Medical Center

Medically reviewed by Ke He, MD (何锞), Deputy Director & Head of Skin & Laser Aesthetics. Last reviewed: 19 September 2026.

This page is patient education, not medical advice, and it does not cite individual studies. Discuss your own case with a qualified clinician. To arrange an assessment at Chongqing West District Hospital, see Contact & Consultation.